Description
The Lewis lab has a long interest in the mechanisms of various aspects of diabetic dyslipidemia, including postprandial lipemia, HDL lowering and hypertriglyceridemia. He has made the novel observation that the intestine, in addition to the liver, overproduces lipoproteins in insulin resistant states. He performs integrative, physiological studies in humans to determine the regulation of intestinal and hepatic lipoprotein particle production by hormones, nutrients and pharmacological agents.
